SOLUBLE GUANYLATE CYCLASE STIMULATORS AND ACTIVATORS: NEW HORIZONS IN THE TREATMENT OF PRIAPISM ASSOCIATED WITH SICKLE CELL DISEASE

Soluble guanylate cyclase stimulators and activators: new horizons in the treatment of priapism associated with sickle cell disease

Priapism, defined as a prolonged and often painful penile erection occurring without sexual stimulation or desire, is a common complication in sickle Eyeliner cell disease (SCD), affecting up to 48% of male patients.This condition presents significant clinical challenges and can lead to erectile dysfunction if not properly managed.Current pharmacol

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Distal femoral replacement in complex revision knee arthroplasty

Revision knee arthroplasty is often complicated Hammers and Mallets by the presence of bone loss, making the use of conventional revision implants impossible, due to inadequate bone stock and ligamentous stability.Distal femoral replacement, although traditionally was developed for salvage surgeries for bone tumours, plays an important role in revi

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Species Identification of Caviar Based on Multiple DNA Barcoding

This study aimed to explore the applicability of DNA barcoding for assessing the authenticity of caviar on the Chinese market.A set of universal COI primers and two sets of designed primers based on COI and D-loop genes were used to identify maternal species of samples from 21 batches of caviar.The results showed that the PCR products from three se

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